May 05, 2010 -- In 1998, G.S. Cosmeceutical USA, Inc. began as a small, home-based operation with a handful of clients and a big dream. Today, the Bay Area-based custom contract manufacturer has proliferated into one of the skincare industry's most highly respected formulators and manufacturers of anti-aging cosmeceuticals, OTC skincare, body care, naturals and organics, and baby care products. The secret to G.S. Cosmeceutical's success? "Integrity and collaboration with the client, staying current with the latest ingredient technology, and lots and lots of hard work," says CEO, President and Chief Scientific Officer Gogi Sangha. On May 5, 2010, G.S. Cosmeceutical marked its 12th anniversary with a festive barbecue luncheon for its 45 employees at the company's 60,000-square-foot Bay Area formulation and manufacturing facility. Despite a hard-hitting recession and many changes to the industry, the FDA-registered, cGMP-compliant custom contract manufacturer has witnessed steady growth over the past 12 years, building its Research and Development team with 6 globally versed chemists and expanding production capacity with a state-of-the-art tube filler installed last year. G.S. Cosmeceutical continues to stay current with unique anti-aging innovations, including the use of plant stem cells and breakthrough skin whiteners. Most recently, the contract manufacturer ramped up its sales/marketing efforts with a heightened trade show and website presence, including a recently produced video, which can be found at www.gscos.com/gogis-promise.com. About G.S. Cosmeceutical USA, Inc. G.S. Cosmeceutical USA, Inc. is a privately-owned contract manufacturing company. Headquartered in Livermore, California, the company is a leader in providing R&D;, manufacturing and warehousing services to physicians, cosmetic entrepreneurs, corporate manufacturers, beauty start-ups and leading professionals in the spa and beauty industry. The company formulates across a broad range of categories, including anti-aging skincare, body care and hair care, organic- and natural-based products, paraben-free cosmetics and over-the-counter (OTC) cosmeceutical products. For additional information, please contact Andrea Sercu, Marketing Manager of G.S. Cosmeceutical USA, Inc. at 925-583-1426 or visit http://www.gscos.com/. ...read more

By Gurpreet "Gogi" SanghaIn the Eighties, antioxidants heralded a new age in skincare with a host of free radical fighters that afforded broad-reaching protection against future signs of aging. Alpha hydroxy acids came along to accelerate exfoliation and rejuvenate skin, while peptides emerged in the late Nineties to gain new ground with preparations that help repair damaged cells, relax wrinkles and build collagen. Today, the arrival of plant stem cells in topical skincare carries a new mission: the ability to not only protect, prevent and repair aging skin cells but to actuallyreplacelost and damaged cells with healthy new skin cells. Already, the applications are yielding dramatic results with newfound promise of revolutionizing the skincare industry in ways never before realized.  An Apple a Day Keeps Signs of Aging Away As we age, the turnover of human epidermal stem cells begins to slow. Over time, these critical cells function less efficiently. Hindered by a finite number of potential cell divisions, lost and dying cells start to outnumber fresh new cells, and, sooner than later, they culminate in signs of aging. Plant stem cells, however, have the ability to divide over many generations and the unique capacity to stimulate and protect human stem cells. The results are a reduction in the appearance of fine lines and wrinkles, collagen loss and other common signs of aging. The most common plant-derived stem cell used in skincare today is the Swiss Uttwiler Spätlauber apple. First cultivated in the 18 century for its hardy, long-lasting fruit, this tannin-rich fruit offers a rich source of anti-aging activity. By forming small wounds in "explants" of the stem cell tissue, scientists are able to stimulate large cell masses known as calluses, which contain the "unprogrammed" and undifferentiated cells of the plant. It is within these "blank canvases" that exciting, new applications in skincare yield promise, including the ability to increase the longevity of human skin cells and stimulate new ones. In a Swiss in-house study published in theSOFW Journalin 2008¹, scientists showed that a 0.1% concentration of stem cells extracted from the Uttwiler Spätlauber apple stimulated the proliferation of human stem cells by 80%. In followup experiments, the scientists irradiated a human stem cell sample with UV light. While nearly half of the cultured stem cells died when exposed to the UV light, the number of living cells grown in the culture containing the apple extract experienced only a small decrease. Further Swiss studies showed that incubating fibroblast cells — the building blocks of collagen and other skin structural tissue proteins — in a 2% Uttwiler Spätlauber apple extract neutralized factors that lead to aging and, in some cases, actually reversed the process.  Additional Plant Stem Cells Showing Promise A wide range of plant stem cells, including extracts from edelweiss, echinacea, gotu kola and several lilac varietals, may offer significant future skincare applications. For instance, edelweiss, an Alpine flower with a special affinity to survive extreme altitudes and solar radiation exposure, offers potent antioxidant and anti-inflammatory benefits. Edelweiss stem cells inhibit the enzymes that break down hyaluronic acid and collagen. To illustrate, a cream with 1% edelweiss stem cells used twice daily reduced wrinkle depth of the eye contour area by 15% after 20 days of treatment in a clinical study involving 20 individuals. The stem cells from echinacea, a botanical revered for its immune-strengthening properties, have also demonstrated an ability to inhibit collagenase, the enzyme that breaks down collagen, while stimulating the synthesis of new collagenin vitro. Likewise, stem cells from the gotu kola plant, also known as tiger grass, have been shown to decrease the skin-degrading enzyme, hyaluronidase, by up to 90% and therefore retain the skin's hyaluronic acid, a key extracellular matrix ingredient responsible for hydration and elasticity. Other plant-derived stem cells may offer new applications in fighting acne.Syringa vulgaris L.,otherwise known as common lilac, has been shown to inhibit 5α-reductase, an enzyme involved in sebum production, as well as decrease the pro-inflammatory chemokine IL-8. In clinical studies, a cream containing 1% of a patented plant stem cell extract reduced lesions in 29 acne patients by 40% in 30 days and showed a significant decrease in inflammation and melanin pigmentation. By combining these plant-derived stem cells with other anti-aging actives, such as peptides, proteins and cell-active folic acid, we can rejuvenate skin cell DNA, the core center for all cell renewal processes, and literally give aging skin a fresh new start. Gurpreet "Gogi" Sangha is the CEO and Chief Scientific Officer of G.S. CosmeceuticalUSA, Inc.,a Livermore, CA-based contract manufacturer of anti-aging skin care, body care, hair care, natural and organic-based products, and OTC cosmeceuticals. G.S. Cosmeceutical provides R&D;, manufacturing and warehousing services to physicians, cosmetic entrepreneurs, corporate manufacturers, beauty start-ups and leading professionals in the spa and beauty industry. For more information about G.S. Cosmeceutical USA, Inc., please visitwww.gscos.comor call 925-583-1426.  Source: Schmid D, Schurch P, Belser E, Zülli F. Plant Stem Extract for Cell Longevity of Skin and Hair.SOFW Journal.2008;134(5):30-5. ...read more

Livermore, CA, January 4, 2010 —G.S. Cosmeceutical USA, Inc.announced today the appointment of Andrea Sercu to Marketing Manager. Reporting to the company's Chief Operating Officer, Gurkirpal Sandhu, Ms. Sercu will develop and implement the corporate marketing strategy to increase G.S. Cosmeceutical's market share, including the research and development of media services and strategies and the creation of corporate sales and marketing collateral. Ms. Sercu will also assume responsibilities for all lead generation, web content and industry communication. Prior to joining G.S. Cosmeceutical, Ms. Sercu held various positions in beauty manufacturing as a marketing communications specialist and corporate copywriter. She offers 15 years' experience in the skincare, cosmetics, haircare and natural products industries as a copywriter, public relations specialist and marketing manager. Throughout her career, she has helped implement strategic marketing campaigns for small and large manufacturers, including Procter&Gamble; Professional Beauty, Joico Laboratories, Cynosure, Silhouet-Tone and more. Her vast network of contacts in the skincare industry includes dayspa and medispa owners, physicians and manufacturers. A graduate of the of the University of Florida Ms. Sercu holds a bachelor's of science in Advertising from the College of Journalism. "We are very excited to welcome Andrea Sercu to theG.S. Cosmeceuticalteam," statesGogi Sangha, CEO and founder of G.S. Cosmeceutical USA, Inc. "Andrea's extensive relationships in the skincare industry and her ability to develop effective, results-oriented marketing plans will serve as an asset to our rapidly expanding company and our clients." For additional information on the release, please contactG.S. Cosmeceutical USA, Inc.or visithttp://www.gscos.com/   About G.S. Cosmeceutical USA, Inc. G.S. Cosmeceutical USA, Inc. is a privately-owned contract manufacturing company. Headquartered in , the company is a leader in providing R&D, manufacturing and warehousing services to physicians, cosmetic entrepreneurs, corporate manufacturers, beauty start-ups and leading professionals in the spa and beauty industry. The company formulates across a broad range of categories, including anti-aging skincare, body care and hair care, organic- and natural-based products, paraben-free cosmetics and over-the-counter (OTC) cosmeceutical products. ...read more