CIALIS ( TADALAFIL ) Cialis is a prescription medicine taken by mouth for the treatment of erectile dysfunction (ED) in men. ED is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection should see his doctor for help if the condition bothers him. Cialis may help a man with ED get and keep an erection when he is sexually excited.  CIALIS ( TADALAFIL ) Description: CIALIS is not for everyone. If you take nitrates, often used for chest pain (also known as angina), or alpha-blockers (other than Flomax 0.4 mg once daily), prescribed for prostate problems or high blood pressure, do not take CIALIS. Such combinations could cause a sudden, unsafe drop in blood pressure. Don't drink alcohol in excess (to a level of intoxication) with CIALIS. This combination may increase your chances of getting dizzy or lowering your blood pressure. CIALIS does not protect a man or his partner from sexually transmitted diseases, including HIV. The most common side effects with CIALIS were headache and upset stomach. Backache and muscle ache were also reported, sometimes with delayed onset. Most men weren't bothered by the side effects enough to stop taking CIALIS. Although a rare occurrence, men who experience an erection for more than 4 hours (priapism) should seek immediate medical attention. Discuss your medical conditions and medications with your doctor to ensure CIALIS is right for you and that you are healthy enough for sexual activity. Individual results may vary. In clinical trials, CIALIS was shown to improve, up to 36 hours after dosing, the ability of men with ED to have a single successful intercourse attempt. CIALIS has not been studied for multiple sexual attempts per dose. Cialis info: Viagra is a breakthrough treatment that improves a man's response to sexual stimulation. 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Purchasing Viagra 100mg tablets on line allows individuals to split the 100mg Viagra Impotence tablets into two 50mg doses for a substantial Impotence savings. Pfizer manufactures the Viagra tablets in 25mg, 50mg and 100mg doses; Impotence however, most clinical physicians Impotence are not cost conscious and write Viagra prescriptions only for the 50mg tablets. By splitting the tablets in half individuals can enjoy a substantial savings. CIALIS ® 20mg / TADALAFIL Cialis ® 20mg film-coated tablets The active substance is tadalafil. Each tablets of Cialis ® contains 20mg of tadalafil. The other ingredients are: Tablet Core: lactose monohydrate, croscarmellose sodium, hydroxypropyl cellulose, microcrystalline cellulose, sodium lauryl sulfate, magnesium stearate. Film-Coat: lactose monohydrate, hypromellose, triacetin, titanium dioxide (E171), iron oxide yellow (E172), talc. WHAT CIALIS IS AND WHAT IS IT USED FOR: Cialis ® comes as yellow film-coated tablets. They are in the shape of almonds and have "C 20" marked on one side. These tablets are available in blister packs containing 2, 4 or 8 tablets. Cialis ® is a treatment for men with erectile dysfunction. This is when a man cannot get, or keep a hard, erect penis suitable for sexual activity. Cialis ® belongs to a group of medicines called phosphodiesterase type 5 inhibitors. Following sexual stimulation Cialis ® works by helping the blood vessels in your penis to relax, allowing the flow of blood into your penis. The result of this is improved erectile function. Cialis ® will not help you if you do not have erectile dysfunction. It is important to note that Cialis ® does not work if there is no sexual stimulation. You and your partner will need to engage in foreplay, just as you would if you were not taking a medicine for erectile dysfunction. BEFORE YOU TAKE CIALIS DO NOT TAKE CIALIS: if you are taking any form of organic nitrate or nitric oxide donors such as amyl nitrite. This is a group of Medicines ("Nitrates") used in the treatment of angina pectoris ("Chest pain"). Cialis ® has been shown to increase the effects of these drugs. If you are taking any form of nitrate or are unsure tell you doctor.  If you have serious heart disease or have had a recent heart attack.  If you have had a recent stroke.  If you have low blood pressure or uncontrolled high blood pressure.  If you are (hypersensitive) allergic to tadalafil or any of the other ingredients of Cialis ®. Take Special care with Cialis ® Sexual activity carries a possible risk to patients with heart disease because it puts an extra strain on your heart. If you have a heart problem you should tell your doctor. The following are reasons why Cialis ® may also not be suitable for you. If any of them apply to you, talk to your doctor before you take the medicine: you have sickle cell anemia (an abnormality of red blood cells), multiple myeloma (cancer of the bone marrow), leukemia (cancer of the blood cells) or any deformation of your penis.  You have a serious liver or kidney problem. Take other medicines: As a general rule, always tell your doctor if you are taking or have recently taken any other medicine, even those not prescribed, because occasionally they might interact. This is particularly important if you are treated with nitrates as you should not take Cialis ® if you are taking these medicines. Do not take Cialis ® with other medicines if your doctor tells you that you may not. You should not use Cialis ® together with any other treatments for erectile dysfunction. Cialis ® is not intended for use by women or by children under the age of 18. Driving and using machines: As dizziness has been reported in men taking Cialis ® in clinical studies, you should be aware of how you react to Cialis ® before you drive or operate machinery. Information for men intolerant of lactose, one of the ingredients of Cialis ®: Cialis ® contains lactose and should not be taken by patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. HOW TO TAKE CIALIS Always take Cialis ® exactly as your doctor has instructed you. You should check with your doctor or pharmacist if you are unsure. The recommended starting dose is one 10mg tablet before sexual activity. If the effect of this dose is too weak your doctor may increase the dose to 20mg. Cialis ® tablets are for oral use. Swallow the tablet whole with some water. You may take Cialis ® with or without food. You may take a Cialis ® tablet at any point in time from 30 minutes to 12 hours before sexual activity. Cialis ® may still be effective up to 24 hours after taking the tablet. It is important to note that Cialis ® does not work if there is no sexual stimulation. You and your partner will need to engage in foreplay, just as you would if you were not taking a medicine for erectile dysfunction. You should NOT take Cialis ® more than once a day. Daily use of Cialis ® is strongly discouraged. If you take more Cialis ® than you should: Tell your doctor. POSSIBLE SIDE EFFECTS Like all medicines, Cialis ® can have side effects. These effects are normally mild to moderate in nature. The most common undesirable effects are headache and indigestion. Less commonly reported side effects are back pain, muscle aches, nasal congestion, facial flushing and dizziness. Uncommon effects are swelling of the eyelids, eye pain and red eyes. If you have any of these side effects and they are troublesome, sever, or do not go away, tell your doctor. Allergic reactions (including skin rashes) could occur. In rare instances it is possible that a prolonged and possibly painful erection may occur after taking Cialis ®. If you have such an erection, which lasts continuously for more than 4 hours, you should contact a doctor immediately. In case of chest pain occurring during or after sexual activity you should NOT use nitrates but you should seek immediate medical assistance. If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist. Heart attack, stroke and irregular heartbeats have been reported rarely in men taking Cialis ®. Most, but not all of these men had known heart problems before taking this medicine. It is not possible to determine whether these events were directly related to Cialis ®. Effects were seen in one animal species that might indicate impairment of fertility. Subsequent studies in man suggest that this effect is unlikely in humans. STORING CIALIS Keep out of reach and sight of children. Store in the original package. Do not use after the expiry date stated on the carton and blister. For More Details:  https://www.powerallpharmacy.ca/index.php?main_page=product_info&cPath=5&products_id=112 Whatsapp: +1 (336) 267-4575 ...read more

COSENTYX®  (secukinumab) Injection, for Subcutaneous Use DESCRIPTION Secukinumab is a recombinant human monoclonal IgG1/κ antibody that binds specifically to IL-17A. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Secukinumab has a molecular mass of approximately 151 kDa; both heavy chains of secukinumab contain oligosaccharide chains. COSENTYX Injection COSENTYX injection is a sterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solution. COSENTYX is supplied in a single-use Sensoready pen with a 27-gauge fixed ½-inch needle, or a single-use prefilled syringe with a 27-gauge fixed ½-inch needle. The removable cap of the COSENTYX Sensoready pen or prefilled syringe contains natural rubber latex. Each COSENTYX Sensoready pen or prefilled syringe contains 150 mg of secukinumab formulated in: L-histidine/histidine hydrochloride monohydrate (3.103 mg), L-methionine (0.746 mg), polysorbate 80 (0.2 mg), trehalose dihydrate (75.67 mg), and Sterile Water for Injection, USP, at pH of 5.8. COSENTYX For Injection COSENTYX for injection is supplied as a sterile, preservative free, white to slightly yellow, lyophilized powder in single-use vials. Each COSENTYX vial contains 150 mg of secukinumab formulated in L-histidine/histidine hydrochloride monohydrate (4.656 mg), polysorbate 80 (0.6 mg), and sucrose (92.43 mg). Following reconstitution with 1 mL Sterile Water for Injection, USP, the resulting pH is approximately 5.8. INDICATIONS Plaque Psoriasis COSENTYX® is indicated for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy. Psoriatic Arthritis COSENTYX is indicated for the treatment of adult patients with active psoriatic arthritis. Ankylosing Spondylitis COSENTYX is indicated for the treatment of adult patients with active ankylosing spondylitis. DOSAGE AND ADMINISTRATION Plaque Psoriasis The recommended dosage is 300 mg by subcutaneous injection at Weeks 0, 1, 2, 3, and 4 followed by 300 mg every 4 weeks. Each 300 mg dosage is given as 2 subcutaneous injections of 150 mg. For some patients, a dosage of 150 mg may be acceptable. Psoriatic Arthritis For psoriatic arthritis patients with coexistent moderate to severe plaque psoriasis, use the dosing and administration recommendations for plaque psoriasis [see DOSAGE AND ADMINISTRATION]. For other psoriatic arthritis patients, administer COSENTYX with or without a loading dosage by subcutaneous injection. The recommended dosage: With a loading dosage is 150 mg at weeks 0, 1, 2, 3, and 4 and every 4 weeks thereafter Without a loading dosage is 150 mg every 4 weeks If a patient continues to have active psoriatic arthritis, consider a dosage of 300 mg. COSENTYX may be administered with or without methotrexate. Ankylosing Spondylitis Administer COSENTYX with or without a loading dosage by subcutaneous injection. The recommended dosage: With a loading dosage is 150 mg at weeks 0, 1, 2, 3, and 4 and every 4 weeks thereafter Without a loading dosage is 150 mg every 4 weeks. Assessment Prior To Initiation Of COSENTYX Evaluate patients for tuberculosis (TB) infection prior to initiating treatment with COSENTYX [see WARNINGS AND PRECAUTIONS]. Important Administration Instructions There are three presentations for COSENTYX (i.e., Sensoready pen, prefilled syringe, and lyophilized powder in vial for reconstitution). The COSENTYX “Instructions for Use” for each presentation contains more detailed instructions on the preparation and administration of COSENTYX [see Instructions for Use]. COSENTYX is intended for use under the guidance and supervision of a physician. Patients may self-inject after proper training in subcutaneous injection technique using the Sensoready pen or prefilled syringe and when deemed appropriate. The lyophilized powder for reconstitution is for healthcare provider use only. Administer each injection at a different anatomic location (such as upper arms, thighs, or any quadrant of abdomen) than the previous injection, and not into areas where the skin is tender, bruised, erythematous, indurated, or affected by psoriasis. Administration of COSENTYX in the upper, outer arm may be performed by a caregiver or healthcare provider. Preparation For Use Of COSENTYX Sensoready® Pen And Prefilled Syringe Before injection, remove COSENTYX Sensoready pen or COSENTYX prefilled syringe from the refrigerator and allow COSENTYX to reach room temperature (15 to 30 minutes) without removing the needle cap. The removable cap of the COSENTYX Sensoready pen and the COSENTYX prefilled syringe contains natural rubber latex and should not be handled by latex-sensitive individuals [see WARNINGS AND PRECAUTIONS]. Inspect COSENTYX visually for particulate matter and discoloration prior to administration. COSENTYX injection is a clear to slightly opalescent, colorless to slightly yellow solution. Do not use if the liquid contains visible particles, is discolored or cloudy. COSENTYX does not contain preservatives; therefore, administer the Sensoready pen or prefilled syringe within 1 hour after removal from the refrigerator. Discard any unused product remaining in the Sensoready pen or prefilled syringe. Reconstitution And Preparation Of COSENTYX Lyophilized Powder COSENTYX lyophilized powder should be prepared and reconstituted with Sterile Water for Injection by a trained healthcare provider using aseptic technique and without interruption. The preparation time from piercing the stopper until end of reconstitution on average takes 20 minutes and should not exceed 90 minutes. -Remove the vial of COSENTYX lyophilized powder from the refrigerator and allow to stand for 15 to 30 minutes to reach room temperature. Ensure the Sterile Water for Injection is at room temperature. -Slowly inject 1 mL of Sterile Water for Injection into the vial containing COSENTYX lyophilized powder and direct the stream of Sterile Water for Injection onto the lyophilized powder. -Tilt the vial at an angle of approximately 45 degrees and gently rotate between the fingertips for approximately 1 minute. Do not shake or invert the vial. -Allow the vial to stand for about 10 minutes at room temperature to allow for dissolution. Note that foaming may occur. -Tilt the vial at an angle of approximately 45 degrees and gently rotate between the fingertips for approximately 1 minute. Do not shake or invert the vial. -Allow the vial to stand undisturbed at room temperature for approximately 5 minutes. The reconstituted COSENTYX solution should be essentially free of visible particles, clear to opalescent, and colorless to slightly yellow. Do not use if the lyophilized powder has not fully dissolved or if the liquid contains visible particles, is cloudy or discolored. Prepare the required number of vials (1 vial for the 150 mg dose or 2 vials for the 300 mg dose). The COSENTYX reconstituted solution contains 150 mg of secukinumab in 1 mL of solution. After reconstitution, use the solution immediately or store in the refrigerator at 2°C to 8°C (36°F to 46°F) for up to 24 hours. Do not freeze. If stored at 2°C to 8°C (36°F to 46°F), allow the reconstituted COSENTYX solution to reach room temperature (15 to 30 minutes) before administration. COSENTYX does not contain preservatives; therefore, administer within 1 hour after removal from 2°C to 8°C (36°F to 46°F) storage. HOW SUPPLIED Dosage Forms And Strengths Injection: 150 mg/mL solution in a single-use Sensoready pen Injection: 150 mg/mL solution in a single-use prefilled syringe For Injection: 150 mg, lyophilized powder in a single-use vial for reconstitution (for healthcare professional use only) COSENTYX Sensoready pen: NDC 0078-0639-41: Carton of two 150 mg/mL (300 mg dose) Sensoready pens (injection) NDC 0078-0639-68: Carton of one 150 mg/mL single-use Sensoready pen (injection) COSENTYX prefilled syringe: NDC 0078-0639-98: Carton of two 150 mg/mL (300 mg dose) single-use prefilled syringes (injection) NDC 0078-0639-97: Carton of one 150 mg/mL single-use prefilled syringe (injection) The removable cap of the COSENTYX Sensoready pen and prefilled syringe contains natural rubber latex. Each Sensoready pen and prefilled syringe is equipped with a needle safety guard. COSENTYX vial (for healthcare professional use only): NDC 0078-0657-61: Carton of one 150 mg lyophilized powder in a single-use vial (for injection) Storage And Handling COSENTYX Sensoready pens, prefilled syringes and vials must be refrigerated at 2°C to 8°C (36°F to 46°F). Keep the product in the original carton to protect from light until the time of use. Do not freeze. To avoid foaming do not shake. COSENTYX does not contain a preservative; discard any unused portion. For More Details:  https://www.powerallpharmacy.ca/index.php?main_page=product_info&cPath=1_8&products_id=185 Whatsapp: +1 (336) 267-4575 ...read more

Xanax is a member of benzodiazepines, which is a group of drugs. Xanax Is used for treatment of various health conditions such as panic disorders, anxiety, and anxiety disorders due to depression. This form of medication may also be used for other purposes which are not indicated in some medication guides. Xanax acts on the nerves and brain (central nervous system) to come up with a calming feeling. It works through improving the effect of a natural body chemical (GABA). This drug is used to treat specific health conditions like repeated anxiety episodes, anxiousness, panic disorder and anxiousness that is associated with depression. It is also effective for treating essential tremor. Before taking this medication, people have to be aware of its effects and appropriate dosage. The dosage depends on the response to your treatment and medical condition. The dose can be increased until the drug starts working effectively. Following the instructions of your physician is highly essential. It will lessen the side effect risks in the future. Xanax Cost Information There are several aspects that may influence the price of Xanax. These prices are usually based without insurance and if you have prescription insurance, you should call the particular pharmacy to verify the exact price. Short-Term Side Effects When it comes to short-term side effects, a person taking Xanax May experience withdrawal symptoms like irritability, restlessness, high blood pressure and breathing rate, vomiting, insomnia, muscle pain, shedding of tears, chills, perspiration and more. Other common side effects are fatigue, depression, lightheadedness, sedation, decreased or increased appetite, decreased salivation, cognitive disorder and even abnormal coordination. These short term side effects will vary from one person to another. Long-Term Side Effects Most drugs usually provide side effects which can be at an intense or mild level. Xanax has been FDA-approved as a short term treatment which normally ranges for about 8 weeks of having a panic disorder. The long term side effects of taking Xanax can be classified into various conditions. These can be paradoxical reactions, physical side effects, psychological side effects, tolerance and brain atrophy. Paradoxical reasons include violent behavior, OCD, paranoia, hallucinations, phobias, aggressiveness, suicidal intentions and nervousness. For physical effects, these can be drowsiness, slurred speech, respiratory changes, memory loss, and confusion. Interactions Xanax can interact with the medications such as: Alprazolam Selected Itraconazole/benzodiazepine Sedative hypnotics Fluvoxamine Cimetidine Lomitapide Ritonavir Boceprevir Ethyl alcohol Clozapine Nefazodone Rifampin Buprenorphine-naloxone Sodium oxybate Midazolam Adderall Nexium (esomeprazole) Synthroid (levothyroxine) Celexa (citalopram) Flexeril (cyclobenzaprine) Prozac (fluoxetine) Cymbalta (duloxetine) Aspirin Ambient (zolpidem) How It Works Xanax Is one of the benzodiazepines and this group of medications provides numerous effects to the body for the person taking any of them. Some of the effects can be stopping seizures, reducing anxiety, relaxing muscles, causing sleepiness and impairing short term memory. It basically works inside the brain through enhancing the GABA (gamma-aminobutyric acid) effects. GABA is a chemical used to create a natural calming feeling. It slows down and prevents nerve signals to your brain. This is one of the main reasons why Xanax as well as other benzodiazepines have been considered as sedatives, mild tranquilizers, or CNS (central nervous system) depressants. For this reason, this form of medication can effectively treat most symptoms caused by conditions such as anxiety and panic disorder. These are just two of many health conditions that can be treated by Xanax. Brand Name Alternatives The generic name for Xanax is Alprazolam. There are still other brand names that refer to Xanax. It has brand names such as Nivaran, Alprazolam Intensol and Xanax XR in the United States. For its Canadian brand alternatives, it is usually labeled as Apo-Alpraz, Novo-Alprazol, Xanax TST, Alti-Alprazolam, Nu-Alpraz and Mylan-Alprazolam. When it comes to Mexican brand names, you may find it labeled as Tazun, Alzam, Neupax, Farmapram, Tafil or Irizz. For More Details:  https://www.powerallpharmacy.ca/index.php?main_page=product_info&cPath=1_9&products_id=27 Whatsapp: +1 (336) 267-4575 ...read more