Huntington's disease Huntington's disease is a neurodegenerativegenetic disorderthat affects muscle coordination and leads to mental decline and behavioral symptoms. It is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability. It is the most common form of disorder which usually appears at the age of thirties and forties. Individuals with the adult-onset form of Huntington disease usually live about 15 to 20 years after signs and symptoms begin. Symptoms The Early signs and symptoms include Slow or abnormal eye movements, impaired gait, posture and balance, Difficulty with the physical production of speech or swallowingirritability,depression, small involuntary movements, poor coordination, and trouble in learning new information or making decisions. Many people develop involuntary jerking or twitching movements affected individuals may have trouble walking, speaking, and swallowing. People with this disorder also experience changes in personality and a decline in thinking and reasoning abilities. Inheritance of Huntington disease The disease is inherited in an autosomal dominant pattern. The altered gene in each cell can cause the disorder. It mainly inherits from one affected parent. In this process the size of the CAG trinucleotide repeat often increases. This leads to early signs and symptoms which known as anticipation. The gene passes from parent to child. It lengthens into the range of 36 repeats. Treatments There's no cure forHuntington's disease. But some of the features of Huntington's disease can be managed with medication and therapies, which may be coordinated by specialist teams.Its progress can't be reversed or slowed down.Speech and language therapy and occupational therapy, can help with communication and day-to-day living. Some of the disciplinary approaches that can be focused on are · Diet and supplements · Exercise · Spiritual and psychosocial support Some of the foods nourish the brain, support memory and build overall immunity are especially recommended.Regular exercise is very important. Once Huntington's disease is confirmed, patients are encouraged to continue a healthy lifestyle approach.Medications are available to treat the symptoms of Huntington's disease.Results of some studies have suggested that valproic acid and clonazepam may be effective in the treatment of chorea, while results of other studies have been less conclusive. Research Efforts The research being done is encouraging in terms of slowing the progression of the disease.Basic neurobiology Investigators in the field of neurobiology have been continuingto study the Huntington's gene for understanding how it causes. Clinical trials have been performed on human for the result ofpotential treatments. View More: Web: http://prasadhospitals.in/ Mail: info@prasadhospitals.in Mobile: +91-8801233333
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